Pyridox 20 | View Uses, Dosage, Price, FAQ
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Pyridox 20 Tablet

Generic: Doxylamine Succinate + Pyridoxine Hydrochloride

Type: Tablet

Pack Size: 10 Pcs

The Pyridoxine Hydrochloride + Doxylamine Succinate combination is indicated for the treatment of nausea and vomiting of pregnancy in women who do not achieve adequate relief with conservative management.

Discount Price: ৳ 86
MRP: ৳ 90 5% Off

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✅ Description:

Doxylamine Succinate is an ethanolamine-class antihistamine that acts by blocking histamine (H1) receptors. It readily crosses the blood–brain barrier and exhibits strong affinity for central H1 receptors. Its antiemetic effect is achieved through inhibition of the vestibular system and muscarinic receptors, thereby reducing stimulation of the vomiting center.

Pyridoxine Hydrochloride (Vitamin B6) is a vitamin B6 analog that possesses anti-nausea properties and plays a supportive role in reducing pregnancy-related nausea and vomiting.

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✔️ Pregnancy & Lactation

Pregnancy Category A: Intended for the treatment of nausea and vomiting of pregnancy when conservative measures are ineffective.

Lactation: Both components are excreted into breast milk; therefore, caution is advised when administered to breastfeeding women.

✔️ Dosage & Administration

Begin treatment with one tablet orally at bedtime (Day 1).

If symptoms are adequately controlled, continue with one tablet daily at bedtime.

If symptoms persist on Day 2, increase the dose to one tablet in the morning and one tablet at bedtime.

Maximum recommended dose: two tablets per day.

Tablets should be taken daily on an empty stomach with a glass of water. Swallow whole; do not crush, chew, or split. This medication should be taken regularly and not on an as-needed basis.

✔️ Drug Interactions

Concomitant use with monoamine oxidase inhibitors (MAOIs) is contraindicated, as MAOIs may intensify and prolong the central nervous system and anticholinergic effects of antihistamines.

Concurrent use with alcohol or other CNS depressants (e.g., sedatives, tranquilizers, hypnotics) is not recommended due to the increased risk of excessive sedation.

✔️ Side Effects

Somnolence

Increased risk of accidents when used with CNS depressants

✔️ This combination is contraindicated in women with:

Known hypersensitivity to Doxylamine Succinate, Pyridoxine Hydrochloride, other ethanolamine-derived antihistamines, or any formulation component

Concurrent use of monoamine oxidase (MAO) inhibitors

✔️ Precautions & Warnings

This medication may cause drowsiness due to the anticholinergic effects of doxylamine. Patients should avoid driving or operating heavy machinery while taking this medicine.

Use is not recommended in women who are consuming alcohol or other CNS depressants.

Due to anticholinergic activity, caution is required in patients with asthma, increased intraocular pressure, narrow-angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, or urinary bladder-neck obstruction.

✔️ Storage:

Store in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.

Frequently Asked Questions (FAQ)

Morning sickness refers to nausea and vomiting commonly experienced during pregnancy. It usually occurs in the first trimester (the first four months), although some women may experience it throughout pregnancy.

Hyperemesis gravidarum is a severe form of pregnancy-related nausea and vomiting. It may lead to dehydration, electrolyte imbalance, and weight loss, and often requires medical attention.

If you or someone else has taken more than the recommended dose, contact your doctor or go to the nearest hospital immediately.

Doxylamine is an antihistamine that blocks histamine, helping to control nausea and vomiting. Pyridoxine (Vitamin B6) helps reduce pregnancy-related nausea by correcting vitamin B6 deficiency and supporting anti-nausea activity.

No. Doxylamine + pyridoxine can pass into breast milk and may cause drowsiness or other effects in the baby. Consult your doctor for safer alternatives while breastfeeding.

Do not increase the dose on your own. If symptoms persist, consult your doctor for further evaluation and treatment adjustment.

No. Do not discontinue the medication without consulting your doctor. Continue taking it for the full duration prescribed to achieve effective symptom control.

Common side effects include: Dizziness Drowsiness Stomach pain Constipation Dry mouth

Your doctor will determine the correct dose based on your condition. Always follow your doctor’s instructions and do not change the dose without medical advice.

Do not use this medicine if you: Are allergic to any of its ingredients Have narrow-angle glaucoma, asthma, bowel obstruction, or stomach ulcers Have severe liver or kidney problems Have taken monoamine oxidase inhibitors (MAOIs) within the last 14 days

Yes. It may cause sleepiness or dizziness. Avoid driving or operating machinery unless you feel fully alert.

Doxylamine + pyridoxine is used to treat nausea and vomiting during pregnancy, especially in women who do not respond to dietary or lifestyle measures.

The most common cause is increased pregnancy-related hormone levels during the early weeks of pregnancy. Nausea may occur in waves and often precedes vomiting, which is the body’s natural response to expel stomach contents.

Yes. When taken exactly as prescribed, it is intended for use during pregnancy and is effective in relieving nausea and vomiting.
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⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

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